Dynamic Secrets and Secret Keys Based Scheme for Securing Last Mile Smart Grid Wireless Communication

An integrated and optimized smart grid cannot be achieved without a secure communication network. Due to the large-scale nature of the power system, the variety of technologies used, and limitations of communication bandwidth, supervisory applications for smart grid still use weak security in many deployments. Adversaries can potentially modify measurement values or inject bad commands over the network. In this paper, we propose a novel scheme based on dynamic secrets and encryption with secret keys. The scheme generates a series of dynamic secrets over the communication network, which are used to generate secret keys for data encryption. The generation of dynamic secret is frequent and no adversary can compromise the network for a longer period, even if he/she knows a secret key. The scheme is secure against eavesdropping, malicious communication injection, man-in-the-middle attack, replay attack, impersonation attack, and chosen-plaintext attack. The security analysis and performance evaluation show that our scheme is feasible to be used in the communication between supervisory and control nodes of various smart grid applications

Authentication protocol for an IoT-enabled LTE networks

The Evolved Packet System-based Authentication and Key Agreement (EPS-AKA) protocol of the long-term evolution (LTE) network does not support Internet of Things (IoT) objects and has several security limitations, including transmission of the object’s (user/device) identity and key set identifier in plaintext over the network, synchronization, large overhead, limited identity privacy, and security attack vulnerabilities. In this article, we propose a new secure and efficient AKA protocol for the LTE network that supports secure and efficient communications among various IoT devices as well as among the users. Analysis shows that our protocol is secure, efficient, and privacy preserved, and reduces bandwidth consumption during authentication

Securing Restricted Publisher-Subscriber Communications in Smart Grid Substations

Smart Grid applications require accurate and correct data transmission from publisher to subscribers with critical communication latency requirements. Since the smart grid is being supported by distributed communication networks, deployed using various wired and wireless technologies, including IP-based networks, securing the communication infrastructure is both critically important and challenging. In this paper, we propose a secure and efficient data delivery scheme, based on a restricted yet dynamic publisher-subscriber architecture, for the published messages from a publisher to the subscribers distributed in the smart grid network. The scheme ensures that the published message is delivered from an authentic publisher to only those authorized subscribers by verifying publisher's signature and access structure of all subscribers. Operation overheads are reduced by performing only one encryption and decryption or hashing per subscriber location using a proxy node as a remote terminal unit. Our analysis shows that the scheme is resistant against replay, man-in-the-middle, and impersonation attacks. Performance evaluation shows that the scheme can support 600 subscribers given the communication latency requirement of 3 ms. We provide the performance of the scheme under different scenarios, and observe that the efficiency of our scheme increases as the ratio of the geographical locations within a substation to the number of subscribers increases

Body composition in Nepalese children using isotope dilution: the production of ethnic-specific calibration equations and an exploration of methodological issues.

Background. Body composition is important as a marker of both current and future health. Bioelectrical impedance (BIA) is a simple and accurate method for estimating body composition, but requires population-specific calibration equations. Objectives. (1) To generate population specific calibration equations to predict lean mass (LM) from BIA in Nepalese children aged 7-9 years. (2) To explore methodological changes that may extend the range and improve accuracy. Methods. BIA measurements were obtained from 102 Nepalese children (52 girls) using the Tanita BC-418. Isotope dilution with deuterium oxide was used to measure total body water and to estimate LM. Prediction equations for estimating LM from BIA data were developed using linear regression, and estimates were compared with those obtained from the Tanita system. We assessed the effects of flexing the arms of children to extend the range of coverage towards lower weights. We also estimated potential error if the number of children included in the study was reduced. Findings. Prediction equations were generated, incorporating height, impedance index, weight and sex as predictors (R (2) 93%). The Tanita system tended to under-estimate LM, with a mean error of 2.2%, but extending up to 25.8%. Flexing the arms to 90° increased the lower weight range, but produced a small error that was not significant when applied to children <16 kg (p 0.42). Reducing the number of children increased the error at the tails of the weight distribution. Conclusions. Population-specific isotope calibration of BIA for Nepalese children has high accuracy. Arm position is important and can be used to extend the range of low weight covered. Smaller samples reduce resource requirements, but leads to large errors at the tails of the weight distribution

2b-RAD genotyping for population genomic studies of Chagas disease vectors: Rhodnius ecuadoriensis in Ecuador

Background: Rhodnius ecuadoriensis is the main triatomine vector of Chagas disease, American trypanosomiasis, in Southern Ecuador and Northern Peru. Genomic approaches and next generation sequencing technologies have become powerful tools for investigating population diversity and structure which is a key consideration for vector control. Here we assess the effectiveness of three different 2b restriction site-associated DNA (2b-RAD) genotyping strategies in R. ecuadoriensis to provide sufficient genomic resolution to tease apart microevolutionary processes and undertake some pilot population genomic analyses. Methodology/Principal findings: The 2b-RAD protocol was carried out in-house at a non-specialized laboratory using 20 R. ecuadoriensis adults collected from the central coast and southern Andean region of Ecuador, from June 2006 to July 2013. 2b-RAD sequencing data was performed on an Illumina MiSeq instrument and analyzed with the STACKS de novo pipeline for loci assembly and Single Nucleotide Polymorphism (SNP) discovery. Preliminary population genomic analyses (global AMOVA and Bayesian clustering) were implemented. Our results showed that the 2b-RAD genotyping protocol is effective for R. ecuadoriensis and likely for other triatomine species. However, only BcgI and CspCI restriction enzymes provided a number of markers suitable for population genomic analysis at the read depth we generated. Our preliminary genomic analyses detected a signal of genetic structuring across the study area. Conclusions/Significance: Our findings suggest that 2b-RAD genotyping is both a cost effective and methodologically simple approach for generating high resolution genomic data for Chagas disease vectors with the power to distinguish between different vector populations at epidemiologically relevant scales. As such, 2b-RAD represents a powerful tool in the hands of medical entomologists with limited access to specialized molecular biological equipment. Author summary: Understanding Chagas disease vector (triatomine) population dispersal is key for the design of control measures tailored for the epidemiological situation of a particular region. In Ecuador, Rhodnius ecuadoriensis is a cause of concern for Chagas disease transmission, since it is widely distributed from the central coast to southern Ecuador. Here, a genome-wide sequencing (2b-RAD) approach was performed in 20 specimens from four communities from Manabí (central coast) and Loja (southern) provinces of Ecuador, and the effectiveness of three type IIB restriction enzymes was assessed. The findings of this study show that this genotyping methodology is cost effective in R. ecuadoriensis and likely in other triatomine species. In addition, preliminary population genomic analysis results detected a signal of population structure among geographically distinct communities and genetic variability within communities. As such, 2b-RAD shows significant promise as a relatively low-tech solution for determination of vector population genomics, dynamics, and spread

Admission profile and discharge outcomes for infants aged less than 6 months admitted to inpatient therapeutic care in 10 countries. A secondary data analysis.

Evidence on the management of acute malnutrition in infants aged less than 6 months (infants <6mo) is scarce. To understand outcomes using current protocols, we analysed a sample of 24 045 children aged 0-60 months from 21 datasets of inpatient therapeutic care programmes in 10 countries. We compared the proportion of admissions, the anthropometric profile at admission and the discharge outcomes between infants <6mo and children aged 6-60 months (older children). Infants <6mo accounted for 12% of admissions. The quality of anthropometric data at admission was more problematic in infants <6mo than in older children with a greater proportion of missing data (a 6.9 percentage point difference for length values, 95% CI: 6.0; 7.9, P < 0.01), anthropometric measures that could not be converted to indices (a 15.6 percentage point difference for weight-for-length z-score values, 95% CI: 14.3; 16.9, P < 0.01) and anthropometric indices that were flagged as outliers (a 2.7 percentage point difference for any anthropometric index being flagged as an outlier, 95% CI: 1.7; 3.8, P < 0.01). A high proportion of both infants <6mo and older children were discharged as recovered. Infants <6mo showed a greater risk of death during treatment (risk ratio 1.30, 95% CI: 1.09; 1.56, P < 0.01). Infants <6mo represent an important proportion of admissions to therapeutic feeding programmes, and there are crucial challenges associated with their care. Systematic compilation and analysis of routine data for infants <6mo is necessary for monitoring programme performance and should be promoted as a tool to monitor the impact of new guidelines on care

Impact evaluation of malicious control commands in cyber-physical smart grids.

The Smart Grid (SG) is vulnerable to cyber-attacks due to its integration with a variety of information, communication and control technologies. If undetected by deployed security systems, cyber-attacks could damage critical power system infrastructure and disrupt service to a very large number of energy customers. In particular, cyber-attackers could hijack the smart grid by injecting malicious commands. To provide insight into these concerns, we propose an approach that develops a new tool for the real-time Cyber-Physical Security Assessment (CPSA) of malicious control commands that target physical SG components. The tool is able to detect and protect the system against known Trojans (such as BlackEnergy). It also efficiently and effectively monitors the health of the power system in real-time and detects the presence of malicious commands. The security analysis of our approach includes a look at three system-generated metrics: system susceptibility, access points, and threat capability. The performance analysis includes a look at the system overhead, scalability, accuracy, robustness, and execution and response time. Our proposed approach was tested on a 42-bus power system with 24 substations. The developed tool could be extended and used by power system operators to assess and mitigate the impact of cyber-attacks on the smart grid

Exercise training enhanced myocardial endothelial nitric oxide synthase (eNOS) function in diabetic Goto-Kakizaki (GK) rats

Abstract Background Different mechanisms of diabetic-induced NO dysfunction have been proposed and central to most of them are significant changes in eNOS function as the rate-limiting step in NO bioavailability. eNOS exists in both monomeric and dimeric conformations, with the dimeric form catalyzing the synthesis of nitric oxide, while the monomeric form catalyzes the synthesis of superoxide (O2-). Diabetic-induced shifts to decrease the dimer:monomer ratio is thought to contribute to the degradation of nitric oxide (NO) bioavailability. Exercise has long been useful in the management of diabetes. Although exercise-induced increases expression of eNOS has been reported, it is unclear if exercise may alter the functional coupling of eNOS. Methods To investigate this question, Goto-Kakizaki rats (a model of type II diabetes) were randomly assigned to a 9-week running program (train) or sedentary (sed) groups. Results Exercise training significantly (p 4), but not in the presence of exogenous BH4. Exercise training also significantly decreased NADPH-dependent O2- activity. Conclusion Exercise-induced increased eNOS dimerization resulted in an increased coupling of the enzyme to facilitate production of NO at the expense of ROS generation. This shift that could serve to decrease diabetic-related oxidative stress, which should serve to lessen diabetic-related complications.</p